All events

Organic Electrochemical Transistors for Analyte Detection

By Sahika Inal, associate professor, Bioscience, Organic Bioelectronics Laboratory, CBRC

Abstract

Conjugated polymers provide a unique toolbox for establishing electrical communication with biological systems. In this talk, I will show how these materials are used in organic electrochemical transistors (OECTs) to detect biological species in physiological media. I will introduce two types of OECT based sensors; one that detects Alzheimer’s disease biomarkers with performance exceeding the state-of-the-art,1,2 and the other that detects coronavirus spike proteins at the physical limit.3 Having challenged these sensors with patient samples, I will discuss areas where proof-of-concept organic biosensor platforms may fail. By tackling each of these problems, we improve device performance to a level that marks a considerable step toward biochemical sensing of infectious and noninfectious disease biomarkers. I will highlight how computational methods can aid in sensor development and organic semiconductor research.

  1. S. Wustoni et al Biosens. Bioelectron. 2019, 143, 111561
  2. A. Koklu et al ACS Nano 2021,15, 8130
  3. K. Guo et al, Nat. Biomed. Eng. 2021, 5, 666

About the speaker

Sahika Inal is an associate professor of bioengineering with affiliations in Electrical Engineering and Materials Science and Engineering at King Abdullah University of Science and Technology (KAUST). She received her B.Sc degree in Textile Engineering from Istanbul Technical University (Turkey), M.Sc in Polymer Science and Ph.D. in Experimental Physics from the University of Potsdam (Germany). She completed her postdoctoral training in the Department of Bioelectronics at the Center of Microelectronics of Provence of the Ecole Nationale Supérieure des Mines de Saint-Étienne (France) under the supervision of George Malliaras. Her expertise is in polymer science and bioelectronic devices, particularly in photophysics of conjugated polymers, characterization of polymer films and the design of biosensors and actuators. Inal lab at KAUST exploits the functionalities of polymers, investigates ion/electron conduction in organic electronic materials, and designs electronic devices that can record/stimulate biological signals. 

KAUST Smart-Health Initiative
March 28, 2021

KAUST Smart-Health Initiative Launch Event
March 28, 2021

The KAUST Smart Health Initiative
WEP 2020,  January 14, 2020
Academic Lecture with Pierre J. Magistretti
The Leap Towards Personalized Medicine and the 4th Industrial Revolution: What’s Coming?
WEP 2020: January 22, 2020
A keynote lecture by Mark Kendall, Entrepreneurial Professor at the Australian National University.

Sci-Café: COVID-19 Part I
April 8, 2020
Featuring panelists Takashi Gojobori, David Ketcheson and Arnab Pain, with moderator Naadiya Carrim
Sci-Café: COVID-19 Part II
April 29, 2020

Featuring panelists Xin Gao, Samir Hamdan and Barry Hogan, with moderator Naadiya Carrim.

Sci-Café: COVID-19 Part III
May 20, 2020
Featuring panelists Peiying Hong, Thomas Anthopoulos and Xiangliang Zhang, with moderator Naadiya Carrim
Sci-Café: COVID-19 Part IV
June 24, 2020
Featuring, panelists Charlotte Hauser, Stefan Arold and Magdy Mahfouz, with moderator Naadiya Carrim
Smart Bandages: A modern way to heal old wounds
May 14, 2018